Table 1 Recent Research Achievements, John Curtin School of Medical Research
From: Competition in health research: the experience of the John Curtin School of Medical Research
Year | Achievement | Researchers(s) | Comment | Reference |
|---|---|---|---|---|
1999 | Heparanase cloned | Hulett, Freeman and colleagues | Inhibiting the enzyme is the basis of cancer treatments based on sulfated polysaccharides | Nature Medicine 5:803-809, 1999 |
2001 | First diabetes susceptibility gene identified | Slattery and colleagues | Serendipitous discovery providing a potential therapeutic target in type 1 diabetes | Proc Nat Acad Sci, USA 98:11533-11538, 2001 |
2002 | Amiloride derivatives block ion channel activity and enhancement of virus-like particle budding caused by an HIV-1 protein | Gage and colleagues | Research on compounds that block viral ion channels raises the possibility of inhibiting viruses that utilize ion channels | Eur. Biophys. J. 31:26-35, 2002 |
2002 | Antibody 'tail sequence' identified that has significant implications for immunological memory | Martin and Goodnow | Finding has wide implications for vaccination, allergy and autoimmunity | Nature Immunology 3:182-188, 2002 |
2002 | Phase II clinical trials of PI 88 anti-cancer drug | Parish and colleagues | Promising results in treating advanced melanoma | Eur. J Cancer 38(S7):74, 2002 |
2003 | New approach to vaccination against cancer | Parish | Approach is potentially less susceptible to immune evasion | Immunology and Cell Biology 81, 106-113, 2003. |